Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | THRA | P10827 | 7/20 | 0.50 |
| ▸ | THRB | P10828 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | RARB | P10826 | 5/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17457887 | 0.92 | HSD17B10 (0.74) | HSD17B10KMT2ATHRATHRBLMNA | |
| SCHEMBL11424105 | 0.87 | HSD17B10 (0.74) | HSD17B10KMT2ATHRATHRBLMNA | |
| SCHEMBL8561241 | 0.84 | LMNA (0.71) | HSD17B10KMT2ALMNARARBALDH1A1 | |
| SCHEMBL963847 | 0.84 | THRA (0.67) | HSD17B10KMT2ATHRATHRBMEN1 | |
| SCHEMBL9258997 | 0.84 | HSD17B10 (0.65) | HSD17B10KMT2ATHRATHRBLMNA | |
| SCHEMBL9253738 | 0.84 | CYP4A11 (0.66) | HSD17B10KMT2ATHRATHRBLMNA | |
| SCHEMBL9818052 | 0.83 | KMT2A (0.73) | HSD17B10KMT2ALMNAMAPTL3MBTL1 | |
| SCHEMBL4185050 | 0.82 | THRA (0.70) | HSD17B10KMT2ATHRATHRBMEN1 | |
| SCHEMBL8383207 | 0.82 | THRA (0.70) | HSD17B10KMT2ATHRATHRBMEN1 | |
| SCHEMBL499485 | 0.82 | THRA (0.70) | HSD17B10KMT2ATHRATHRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596802-B1 | Erythromycin derivatives, their process of preparation and their application as medicaments | ROUSSEL UCLAF (FR) | 1996-03-20 | — | — | EP | disclosed |
| EP-0596802-A1 | Erythromycin derivatives, their process of preparation and their application as medicaments | ROUSSEL UCLAF (FR) | 1994-05-11 | — | — | EP | disclosed |