Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8371908 | 0.76 | MEN1 (0.49) | SIGMAR1MEN1KMT2AL3MBTL1POLB | |
| SCHEMBL5306298 | 0.76 | HTR2A (0.51) | SIGMAR1MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL27663951 | 0.76 | SIGMAR1 (0.48) | SIGMAR1MEN1KMT2AL3MBTL1NPC1 | |
| Hydrochloric Acid SCHEMBL10766746 | 0.75 | MEN1 (0.51) | SIGMAR1MEN1KMT2AL3MBTL1POLB | |
| SCHEMBL1045802 | 0.73 | DRD2 (0.58) | SIGMAR1MEN1KMT2AL3MBTL1POLB | |
| Hydrochloric Acid SCHEMBL8371863 | 0.73 | MEN1 (0.49) | SIGMAR1MEN1KMT2AL3MBTL1POLB | |
| SCHEMBL4953314 | 0.68 | CTSD (0.32) | SIGMAR1 | |
| SCHEMBL8845675 | 0.68 | SIGMAR1 (0.59) | SIGMAR1MEN1KMT2AL3MBTL1POLB | |
| SCHEMBL31438227 | 0.68 | SIGMAR1 (0.59) | SIGMAR1MEN1KMT2AL3MBTL1POLB | |
| SCHEMBL28079976 | 0.67 | L3MBTL1 (0.56) | SIGMAR1MEN1KMT2AL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545425-B1 | 2-(3-Phenylpropyl)hydrazines, intermediates in and a process for the preparation thereof, and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1996-03-20 | — | — | EP | disclosed |
| US-5268468-A | Or optical isomers thereof | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-12-07 | — | — | US | disclosed |
| US-5268468-A | Or optical isomers thereof | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-12-07 | — | — | US | disclosed |
| US-5229417-A | Obsessive compulsive disorders | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-07-20 | — | — | US | disclosed |
| EP-0545425-A1 | 2-(3-Phenylpropyl)hydrazines, intermediates in and a process for the preparation thereof, and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-06-09 | — | — | EP | disclosed |