Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976113 | 0.81 | CYP1A2 (0.40) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL8975796 | 0.76 | DDB1 (0.34) | KDM4EMAPTMEN1KMT2ANR1I2 | |
| SCHEMBL8975764 | 0.71 | FEN1 (0.40) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL8975983 | 0.65 | MAOA (0.43) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL8976111 | 0.64 | ADORA3 (0.43) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL9301263 | 0.64 | CCR1 (0.33) | CCR1 | |
| SCHEMBL4308231 | 0.60 | CCR1 (0.35) | ALDH1A1CCR1 | |
| SCHEMBL9445867 | 0.60 | PKLR (0.40) | KDM4EMAPTALDH1A1 | |
| SCHEMBL26097277 | 0.60 | NOTUM (0.52) | MAPTCCR1MEN1KMT2A | |
| SCHEMBL8976156 | 0.60 | ACHE (0.43) | KDM4EMAPTALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532261-A | TREATING STAPHYLOCOCCUS INFECTIONS | MERCK & CO., INC. (US) | 1996-07-02 | — | — | US | disclosed |