SCHEMBL8976185

SCHEMBL8976185

Cc1cccc(CC2CO2)c1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
TRPA1 O75762 1/20 0.42
GLA P06280 1/20 0.40
GABRA1 P14867 3/20 0.38
GABRB2 P47870 3/20 0.38
CA12 O43570 2/20 0.37
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA9 Q16790 2/20 0.37
PKM P14618 1/20 0.37
HTT P42858 1/20 0.37
KDM4E B2RXH2 1/20 0.36
HPGD P15428 1/20 0.36
HSD17B10 Q99714 1/20 0.36
EGFR P00533 2/20 0.35
ERBB2 P04626 2/20 0.35
MAP3K14 Q99558 1/20 0.35
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5437476 0.88 GABRA1 (0.43) ALDH1A1GLAGABRA1GABRB2TP53
SCHEMBL27625174 0.84 GABRA1 (0.61) ALDH1A1GABRA1GABRB2TP53CYP3A4
SCHEMBL14248992 0.81 ALDH1A1 (0.42) ALDH1A1TRPA1GLAHSD17B10TP53
SCHEMBL7049331 0.80 ALDH1A1 (0.48) ALDH1A1GLATSHRDRD2DRD1
SCHEMBL28335494 0.80 ALDH1A1 (0.48) ALDH1A1GLATSHRDRD2DRD1
SCHEMBL31438264 0.80 ALDH1A1 (0.48) ALDH1A1GLATSHRDRD2DRD1
SCHEMBL13116361 0.80 HSP90AA1 (0.45) ALDH1A1CA1PKMEGFRERBB2
SCHEMBL27683451 0.80 TRPA1 (0.45) ALDH1A1TRPA1GLAGABRA1GABRB2
SCHEMBL31498329 0.80 TRPA1 (0.45) ALDH1A1TRPA1GLAGABRA1GABRB2
SCHEMBL5795157 0.80 CA2 (0.37) ALDH1A1GLAGABRA1GABRB2CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190100502-A1 2-(2,3-EPOXYPROPYL)PHENOL COMPOSITION AND METHOD OF MAKING SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2019-04-04 US claimed
US-20170260152-A1 2-(2,3-EPOXYPROPYL)PHENOL COMPOSITION AND METHOD OF MAKING SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2017-09-14 US claimed
EP-3186235-A2 2-(2,3-EPOXYPROPYL)PHENOL COMPOSITION AND METHOD OF MAKING SABIC Global Technologies B.V. (NL) 2017-07-05 EP claimed
CN-106660978-A 2-(2,3-epoxypropyl)phenol composition and method of making 沙特基础工业全球技术有限公司 2017-05-10 CN claimed
WO-2016032997-A2 2-(2,3-EPOXYPROPYL)PHENOL COMPOSITION AND METHOD OF MAKING SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-03-03 WO claimed
US-20190100502-A1 2-(2,3-EPOXYPROPYL)PHENOL COMPOSITION AND METHOD OF MAKING SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2019-04-04 US disclosed
US-20190100502-A1 2-(2,3-EPOXYPROPYL)PHENOL COMPOSITION AND METHOD OF MAKING SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2019-04-04 US disclosed
US-20170260152-A1 2-(2,3-EPOXYPROPYL)PHENOL COMPOSITION AND METHOD OF MAKING SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2017-09-14 US disclosed
US-20170260152-A1 2-(2,3-EPOXYPROPYL)PHENOL COMPOSITION AND METHOD OF MAKING SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2017-09-14 US disclosed
EP-3186235-A2 2-(2,3-EPOXYPROPYL)PHENOL COMPOSITION AND METHOD OF MAKING SABIC Global Technologies B.V. (NL) 2017-07-05 EP disclosed
EP-3186235-A2 2-(2,3-EPOXYPROPYL)PHENOL COMPOSITION AND METHOD OF MAKING SABIC Global Technologies B.V. (NL) 2017-07-05 EP disclosed
CN-106660978-A 2-(2,3-epoxypropyl)phenol composition and method of making 沙特基础工业全球技术有限公司 2017-05-10 CN disclosed
CN-106660978-A 2-(2,3-epoxypropyl)phenol composition and method of making 沙特基础工业全球技术有限公司 2017-05-10 CN disclosed
WO-2016032997-A3 2-(2,3-EPOXYPROPYL)PHENOL COMPOSITION AND METHOD OF MAKING SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-06-16 WO disclosed
WO-2016032997-A2 2-(2,3-EPOXYPROPYL)PHENOL COMPOSITION AND METHOD OF MAKING SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-03-03 WO disclosed
WO-2016032997-A2 2-(2,3-EPOXYPROPYL)PHENOL COMPOSITION AND METHOD OF MAKING SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-03-03 WO disclosed
US-5480905-A ANTIDEPRESSANTS, ANXIOLYTIC AGENTS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1996-01-02 US disclosed
EP-0565732-A1 BENZODIOXANE DERIVATIVE Chugai Seiyaku Kabushiki Kaisha (JP) 1993-10-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170260152-A1 2-(2,3-EPOXYPROPYL)PHENOL COMPOSITION AND METHOD OF MAKING CYP2J2, HMOX2, PRDX2 ALDH1A1 795/4885TRPA1 4113/4885GLA 2249/4885
US-20190100502-A1 2-(2,3-EPOXYPROPYL)PHENOL COMPOSITION AND METHOD OF MAKING SCO2, HMOX2, PRDX2 ALDH1A1 846/4885TRPA1 3927/4885GLA 2114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.