SCHEMBL8976187

SCHEMBL8976187

Cc1c(C(=O)OCc2ccccc2)c(O)cc2c1C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
RAB9A P51151 5/20 0.44
NPC1 O15118 3/20 0.44
KMT2A Q03164 3/20 0.44
MAPT P10636 5/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
LMNA P02545 2/20 0.43
ALDH1A1 P00352 1/20 0.43
STAT1 P42224 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
MAPK1 P28482 1/20 0.42
SLC6A2 P23975 1/20 0.41
SLC6A3 Q01959 1/20 0.41
SLC37A4 O43826 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
USP2 O75604 1/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8976719 0.80 KDM4E (0.41) TDP1L3MBTL1KMT2AMAPTSMN1; SMN2
SCHEMBL8976457 0.79 MAPT (0.55) TDP1L3MBTL1KMT2AMAPTSMN1; SMN2
SCHEMBL8976225 0.79 PRKCZ (0.47) TDP1L3MBTL1RAB9ANPC1KMT2A
SCHEMBL8976204 0.78 MEN1 (0.49) TDP1L3MBTL1RAB9ANPC1KMT2A
SCHEMBL8952406 0.76 SLC37A4 (0.58) TDP1KMT2AMAPTSMN1; SMN2LMNA
SCHEMBL9741945 0.73 TDP1 (0.62) TDP1L3MBTL1RAB9ANPC1KMT2A
SCHEMBL1129779 0.72 CYP3A4 (0.67) TDP1L3MBTL1RAB9ANPC1KMT2A
SCHEMBL31638730 0.71 TDP1 (0.53) TDP1L3MBTL1RAB9ANPC1KMT2A
SCHEMBL17965761 0.71 TDP1 (0.61) TDP1L3MBTL1RAB9ANPC1KMT2A
SCHEMBL7538283 0.70 LMNA (0.56) TDP1L3MBTL1RAB9ANPC1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0602027-B1 SYNTHESIS OF CARMINIC ACID AND PRINCIPAL INTERMEDIATES EUROP COLOUR PLC (GB) 1996-03-27 EP disclosed
US-5424421-A Synthesis of carminic acid and principal intermediates EUROPEAN COLOUR PLC (GB) 1995-06-13 US disclosed