SCHEMBL8977359

SCHEMBL8977359

C[S+]([O-])c1nc2cc(-n3cccc3)c(F)cc2[nH]1.[LiH]

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 7/20 0.36
FGFR1 P11362 1/20 0.31
FGFR2 P21802 1/20 0.31
FGFR3 P22607 1/20 0.31
HRH4 Q9H3N8 2/20 0.30
HRH3 Q9Y5N1 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8977332 0.75 OPRL1 (0.37) OPRL1
SCHEMBL8977368 0.75 OPRL1 (0.37) OPRL1
SCHEMBL8977408 0.71 ATP4A (0.43)
SCHEMBL8977272 0.71 ATP4A (0.42)
SCHEMBL11355886 0.69 KDM4E (0.51)
SCHEMBL8977361 0.69 SARM1 (0.41)
SCHEMBL8977372 0.69 GRIA1 (0.35) OPRL1
SCHEMBL8977340 0.69 GRIA1 (0.35) OPRL1
SCHEMBL8977271 0.69 ATP1A1 (0.34)
SCHEMBL9790100 0.66 ALDH1A1 (0.48) FGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5554631-A ANTIULCER IL-YANG PHARM. CO., LTD. (KR) 1996-09-10 US disclosed