Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CTH | P32929 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL805874 | 0.79 | LMNA (0.57) | HTTNPC1RAB9APKMKDM4E | |
| SCHEMBL4399385 | 0.79 | EPHX1 (0.52) | HTTSMN1; SMN2RAB9AKDM4EALDH1A1 | |
| SCHEMBL15510403 | 0.79 | MAPT (0.74) | SMN1; SMN2PKMKDM4EALDH1A1MAPT | |
| SCHEMBL4629048 | 0.79 | RAB9A (0.54) | SMN1; SMN2NPC1RAB9APKMKDM4E | |
| SCHEMBL1286315 | 0.78 | PHGDH (0.71) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL11186307 | 0.78 | PKM (0.69) | SMN1; SMN2NPC1RAB9APKMKDM4E | |
| Iodide SCHEMBL2779572 | 0.77 | RAB9A (0.53) | SMN1; SMN2NPC1RAB9APKMKDM4E | |
| Hydrochloric Acid SCHEMBL27651012 | 0.77 | PHGDH (0.68) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL14031230 | 0.76 | MAPT (0.61) | PKMKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL11156215 | 0.76 | ALDH1A1 (0.57) | SMN1; SMN2NPC1PKMKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510344-A | Acrylate fungicides | SCHERING AGROCHEMICALS LIMITED (GB) | 1996-04-23 | — | — | US | disclosed |
| EP-0378308-B1 | Acrylate fungicides | AGREVO UK LTD (GB) | 1996-04-10 | — | — | EP | disclosed |
| US-5332752-A | Acrylate fungicides | SCHERING AGROCHEMICALS LIMITED (GB) | 1994-07-26 | — | — | US | disclosed |
| EP-0378308-A1 | Acrylate fungicides | AgrEvo UK Limited (GB) | 1990-07-18 | — | — | EP | disclosed |
| US-3992391-A | PREVENTION AND TREATMENT OF HYPOXIA | DAINIPPON PHARMACEUTICAL CO., LTD. (JA) | 1976-11-16 | — | — | US | disclosed |