Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MPI | P34949 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PDE4A | P27815 | 3/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12768570 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1GAAMPIAPOBEC3G | |
| SCHEMBL27846632 | 0.72 | HPGDS (0.53) | KDM4EALDH1A1GAAMPIGFER | |
| SCHEMBL187940 | 0.71 | ALDH1A1 (0.54) | KDM4EALDH1A1GAAMPIGFER | |
| SCHEMBL8978590 | 0.71 | DCUN1D1 (0.57) | KDM4EALDH1A1GAAGFERAPOBEC3G | |
| SCHEMBL8840880 | 0.71 | PDE4A (0.67) | KDM4EALDH1A1GAAMPIGFER | |
| SCHEMBL3343223 | 0.70 | NPC1 (0.49) | KDM4EALDH1A1GAAMPIGFER | |
| SCHEMBL8978546 | 0.70 | KDM4E (0.68) | KDM4EALDH1A1GFERAPOBEC3GTDP1 | |
| SCHEMBL15117081 | 0.69 | NR1H2 (0.63) | KDM4EALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL11603170 | 0.69 | ALOX5 (0.74) | KDM4EALDH1A1GAAMPIGFER | |
| SCHEMBL5510771 | 0.68 | ALDH1A1 (0.39) | KDM4EALDH1A1GAAMPIAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489598-A | INHIBITS ADHESION OF MAC-1 TO ENDOTHELIAL CELLS, USEFUL FOR TREATING GASTRITIS INDUCED BY NONSTEROIDANTIINFLAMMATORY DRUGS IMFLAMMATORY BOWEL DISEASE OF ULCERATIVE COLITIS | WARNER-LAMBERT COMPANY (US) | 1996-02-06 | — | — | US | disclosed |