SCHEMBL8979372

SCHEMBL8979372

O=Cc1c(Cl)cc(C(=O)Cl)cc1Cl

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
TDP1 Q9NUW8 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
TTR P02766 1/20 0.37
TSHR P16473 1/20 0.35
ERN1 O75460 2/20 0.33
SRD5A2 P31213 1/20 0.31
KMO O15229 2/20 0.31
TPMT P51580 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3069036 0.82 TTR (0.58) ALDH1A1TDP1MEN1KMT2ATTR
SCHEMBL10921198 0.75 TTR (0.48) ALDH1A1MEN1KMT2ATTRTSHR
SCHEMBL983196 0.75 HPGD (0.46) ALDH1A1TTRTSHRSRD5A2KMO
SCHEMBL15320957 0.75 ALDH1A1 (0.48) ALDH1A1TDP1MEN1KMT2ATSHR
SCHEMBL209239 0.73 HSD17B10 (0.50) ALDH1A1TDP1MEN1KMT2ATTR
SCHEMBL104060 0.73 ALDH1A1 (0.54) ALDH1A1MEN1KMT2ATTRTSHR
SCHEMBL4903616 0.73 TTR (0.65) ALDH1A1MEN1KMT2ATTRTSHR
SCHEMBL9473685 0.72 ERN1 (0.42) ALDH1A1TDP1MEN1KMT2ATSHR
SCHEMBL94930 0.72 ALDH1A1 (0.55) ALDH1A1TDP1MEN1KMT2ATSHR
SCHEMBL14933684 0.71 UNG (0.43) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0604019-B1 N-Acetonylbenzamides and their use as fungicides ROHM & HAAS (US) 1996-05-08 EP disclosed
EP-0604019-A1 N-Acetonylbenzamides and their use as fungicides ROHM AND HAAS COMPANY (US) 1994-06-29 EP disclosed
US-5254584-A Controlling phytopathogens ROHM AND HAAS COMPANY (US) 1993-10-19 US disclosed