SCHEMBL8979899

SCHEMBL8979899

CCN(c1cccc(SCc2ccccc2)n1)S(=O)(=O)C(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.38
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
PKM P14618 1/20 0.37
KMT2A Q03164 1/20 0.37
HPGD P15428 2/20 0.36
TSHR P16473 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 1/20 0.36
HTT P42858 1/20 0.36
RAB9A P51151 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
POLB P06746 1/20 0.36
S100A4 P26447 1/20 0.35
CXCR2 P25025 6/20 0.35
SLC6A4 P31645 1/20 0.35
ELANE P08246 1/20 0.34
ALDH1A1 P00352 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8979869 0.91 PTGS2 (0.36) PTGS2LMNAMAPTPKMKMT2A
SCHEMBL8979865 0.89 PTGS2 (0.37) PTGS2LMNAMAPTPKMKMT2A
SCHEMBL8979765 0.86 ALDH1A1 (0.44) PTGS2LMNAMAPTPKMKMT2A
SCHEMBL8979914 0.86 KMT2A (0.39) PTGS2LMNAMAPTPKMKMT2A
SCHEMBL27377746 0.68 PKM (0.38) LMNAMAPTPKMKMT2AHPGD
SCHEMBL8979773 0.68 HPGD (0.52) PTGS2LMNAMAPTPKMKMT2A
SCHEMBL27406440 0.67 SLC6A4 (0.50) LMNAMAPTPKMKMT2AHPGD
SCHEMBL31404939 0.66 LMNA (0.50) LMNAMAPTPKMKMT2AHPGD
SCHEMBL2408695 0.66 LMNA (0.50) LMNAMAPTPKMKMT2AHPGD
SCHEMBL8979796 0.66 CXCR2 (0.53) PTGS2LMNAMAPTPKMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1038012-C Substiuted pyridinesulfonamide compound or its salt, process for preparing same, and herbicide coutaining same ISHIHARA SANGYO KAISHA (JP) 1998-04-15 CN disclosed
US-5583231-A HERBICIDE ISHIHARA SANGYO KAISHA, LTD. (JP) 1996-12-10 US disclosed
US-5457084-A Herbicides use at low dosage ISHIHARA SANGYO KAISHA LTD. (JP) 1995-10-10 US disclosed
EP-0496608-B1 Substituted pyridinesulfonamide compound or its salt, process for preparing the same, and herbicide containing the same ISHIHARA SANGYO KAISHA (JP) 1995-09-20 EP disclosed
US-5348933-A Triazine substituted compounds ISHIHARA SANGYO KAISHA, LTD. (JP) 1994-09-20 US disclosed
CN-1077453-A Substituted pyridinesulfonamide compound or its salt prepare its method and the weedicide that contains it ISHIHARA SANGYO KAISHA (JP) 1993-10-20 CN disclosed
EP-0562731-A1 Substituted pyridinesulfonamide compounds or their salts, process for preparing the same, and herbicides containing the same ISHIHARA SANGYO KAISHA, Ltd. (JP) 1993-09-29 EP disclosed
EP-0496608-A1 Substituted pyridinesulfonamide compound or its salt, process for preparing the same, and herbicide containing the same ISHIHARA SANGYO KAISHA, Ltd. (JP) 1992-07-29 EP disclosed