Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 3/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13264694 | 0.91 | ESR1 (0.53) | CYP24A1ESR1ESR2MEN1KMT2A | |
| SCHEMBL13543175 | 0.84 | FFAR1 (0.51) | CYP24A1KMT2AALDH1A1LMNACYP1A2 | |
| SCHEMBL11978603 | 0.84 | CYP24A1 (0.51) | CYP24A1MEN1KMT2AALDH1A1HDAC2 | |
| SCHEMBL19520425 | 0.83 | KDM4E (0.47) | ESR1ESR2MEN1KMT2AKDM4E | |
| SCHEMBL18757276 | 0.83 | ESR1 (0.45) | ESR1ESR2MEN1KMT2AKDM4E | |
| SCHEMBL24111761 | 0.82 | NR1H4 (0.53) | CYP24A1CYP2C19LMNAPOLBGAA | |
| SCHEMBL454778 | 0.82 | PLAAT3 (0.51) | CYP24A1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL27851354 | 0.82 | CYP24A1 (0.50) | CYP24A1LMNAPOLBTAAR1 | |
| SCHEMBL8153818 | 0.82 | ALDH1A1 (0.61) | CYP24A1MEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL12680298 | 0.81 | CYP24A1 (0.49) | CYP24A1MAPK1ALDH1A1THRBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11197878-B2 | Anti-inflammatory composition including novel quercetin-based compound | AMOREPACIFIC CORPORATION (KR) | 2021-12-14 | — | — | US | disclosed |
| US-20210145853-A1 | ANTI-INFLAMMATORY COMPOSITION INCLUDING NOVEL QUERCETIN-BASED COMPOUND | AMOREPACIFIC CORPORATION (KR) | 2021-05-20 | — | — | US | disclosed |
| US-10975120-B2 | Site-specific chemoenzymatic protein modifications | NOVARTIS AG (CH) | 2021-04-13 | — | — | US | disclosed |
| US-20190300570-A1 | SITE-SPECIFIC CHEMOENZYMATIC PROTEIN MODIFICATIONS | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. | 2019-10-03 | — | — | US | disclosed |
| US-20190185518-A9 | WARHEAD-CONTAINING PEPTIDOMIMETIC MACROCYCLES AS MODULATORS OF BFL-1 | AILERON THERAPEUTICS, INC. | 2019-06-20 | — | — | US | disclosed |
| US-10023613-B2 | Peptidomimetic macrocycles as modulators of MCL-1 | AILERON THERAPEUTICS, INC. (US) | 2018-07-17 | — | — | US | disclosed |
| US-20170107252-A1 | PEPTIDOMIMETIC MACROCYCLES AS MODULATORS OF MCL-1 | AILERON THERAPEUTICS, INC. | 2017-04-20 | — | — | US | disclosed |
| US-20170037105-A1 | PEPTIDOMIMETIC MACROCYCLES | AILERON THERAPEUTICS, INC. | 2017-02-09 | — | — | US | disclosed |
| US-20170037105-A1 | PEPTIDOMIMETIC MACROCYCLES | AILERON THERAPEUTICS, INC. | 2017-02-09 | — | — | US | disclosed |
| US-20160237116-A1 | SITE-SPECIFIC CHEMOENZYMATIC PROTEIN MODIFICATIONS | NOVARTIS AG | 2016-08-18 | — | — | US | disclosed |
| US-9359400-B2 | Site-specific chemoenzymatic protein modifications | NOVARTIS AG (CH) | 2016-06-07 | — | — | US | disclosed |
| US-5558978-A | Photoresist compositions containing copolymers having acid-labile groups and recurring units derived from either N-(hydroxymethyl)maleimide or N-(acetoxymethyl)maleimide or both | OCG MICROELECTRONIC MATERIALS, INC. (US) | 1996-09-24 | — | — | US | disclosed |
| EP-0659781-A2 | Copolymers of maleimide, for photoresists | OCG Microelectronic Materials Inc. (US) | 1995-06-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210145853-A1 | ANTI-INFLAMMATORY COMPOSITION INCLUDING NOVEL QUERCETIN-BASED COMPOUND | TEAD4, TEAD3, TEAD2 | CYP24A1 2227/4885ESR1 3641/4885ESR2 3091/4885 |
| US-10023613-B2 | Peptidomimetic macrocycles as modulators of MCL-1 | MCL1, BCL2L1, BCL2L11 | CYP24A1 4796/4885ESR1 4154/4885ESR2 2923/4885 |
| US-20190300570-A1 | SITE-SPECIFIC CHEMOENZYMATIC PROTEIN MODIFICATIONS | PTMS, TGM3, TGM1 | CYP24A1 4692/4885ESR1 3713/4885ESR2 3956/4885 |
| US-20170037105-A1 | PEPTIDOMIMETIC MACROCYCLES | GHRHR, GHSR, GHITM | CYP24A1 279/4885ESR1 470/4885ESR2 293/4885 |
| US-20190185518-A9 | WARHEAD-CONTAINING PEPTIDOMIMETIC MACROCYCLES AS MODULATORS OF BFL-1 | BCL2L11, BCL2L1, BCL2L13 | CYP24A1 4169/4885ESR1 2650/4885ESR2 1040/4885 |
| US-20160237116-A1 | SITE-SPECIFIC CHEMOENZYMATIC PROTEIN MODIFICATIONS | PTMS, TGM3, TGM1 | CYP24A1 4692/4885ESR1 3713/4885ESR2 3956/4885 |
| US-10975120-B2 | Site-specific chemoenzymatic protein modifications | PTMS, TGM3, TGM1 | CYP24A1 4692/4885ESR1 3713/4885ESR2 3956/4885 |
| US-11197878-B2 | Anti-inflammatory composition including novel quercetin-based compound | TEAD4, TEAD3, TEAD2 | CYP24A1 2227/4885ESR1 3641/4885ESR2 3091/4885 |
| US-20170107252-A1 | PEPTIDOMIMETIC MACROCYCLES AS MODULATORS OF MCL-1 | MCL1, BCL2L1, BCL2L11 | CYP24A1 4796/4885ESR1 4154/4885ESR2 2923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.