Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8573189 | 0.77 | MAOB (0.40) | DPP4NOTUMALPL | |
| SCHEMBL8980735 | 0.74 | DPP4 (0.39) | DPP4ALPL | |
| SCHEMBL8368757 | 0.73 | KDM4E (0.35) | — | |
| SCHEMBL8981041 | 0.71 | HEXA (0.38) | MEN1KMT2A | |
| SCHEMBL9494868 | 0.69 | PARP1 (0.40) | — | |
| SCHEMBL8980596 | 0.68 | IMPDH2 (0.37) | MEN1KMT2A | |
| SCHEMBL6947117 | 0.67 | TSHR (0.41) | MEN1KMT2A | |
| SCHEMBL8636633 | 0.67 | MAPT (0.41) | KMT2A | |
| SCHEMBL8641729 | 0.67 | MAOA (0.45) | — | |
| SCHEMBL9375600 | 0.66 | ADAM17 (0.46) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711286-A1 | BENZOXAZINONES AND BENZOTHIAZINONES ENDOWED WITH THERAPEUTIC ACTIVITY | ITALFARMACO S.p.A. (IT) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004048-A1 | BENZOXAZINONES AND BENZOTHIAZINONES ENDOWED WITH THERAPEUTIC ACTIVITY | ITALFARMACO S.P.A. (IT) | 1995-02-09 | — | — | WO | disclosed |