SCHEMBL898314

SCHEMBL898314

O=C(NCc1ccc(O)c(O)c1)c1ccc(O)cc1O

nearest known ligand 0.65

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.62
ALPL P05186 1/20 0.62
ERCC1 P07992 7/20 0.59
ERCC4 Q92889 7/20 0.59
ALDH1A1 P00352 1/20 0.56
GFER P55789 1/20 0.56
ALPG P10696 1/20 0.52
POLA1 P09884 1/20 0.52
PIM1 P11309 1/20 0.51
ESR1 P03372 1/20 0.49
SHBG P04278 1/20 0.49
ESR2 Q92731 1/20 0.49
MT-CO2 P00403 1/20 0.48
TRPV1 Q8NER1 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29535664 1.00 ALOX15 (0.62) ALOX15ALPLERCC1ERCC4ALDH1A1
SCHEMBL1529028 0.93 ALOX15 (0.55) ALOX15ALPLERCC1ERCC4ALDH1A1
SCHEMBL28306080 0.85 ALOX15 (0.67) ALOX15ALPLALDH1A1GFER
SCHEMBL29085521 0.83 ALPL (0.49) ALOX15ALPLALDH1A1
SCHEMBL898313 0.83 PTPN7 (0.54) ALOX15ALDH1A1
SCHEMBL5065588 0.83 TRPV1 (0.59) ALOX15ALPLALDH1A1TRPV1
SCHEMBL2267873 0.83 HSP90AA1 (0.64) ALDH1A1GFER
SCHEMBL899105 0.82 PTPN7 (0.53) ALOX15ALDH1A1
SCHEMBL899104 0.82 PTPN7 (0.53) ALOX15ALDH1A1
SCHEMBL23796256 0.81 ERCC1 (0.63) ALPLERCC1ERCC4ALPGPIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108366597-B Substance mixture 西姆莱斯有限公司 2022-09-02 CN claimed
EP-3383200-B1 COMPOSITIONS SYMRISE AG (DE) 2019-11-06 EP claimed
US-20190289886-A1 SUBSTANCE MIXTURES SYMRISE AG (DE) 2019-09-26 US claimed
EP-3470464-A1 LAYER COMPOSITIONS WITH IMPROVED ELECTRICAL PARAMETERS COMPRISING PEDOT/PSS AND A STABILIZER Heraeus Deutschland GmbH & Co KG (DE) 2019-04-17 EP claimed
CN-108366597-A Mixture of substances 西姆莱斯有限公司 2018-08-03 CN claimed
EP-2008530-B1 Aroma composition for reducing or suppressing unwanted bitter and astringent impressions SYMRISE AG (DE) 2011-01-19 EP claimed
US-20080317923-A1 AROMA COMPOSITION FOR REDUCING OR SUPPRESSING AN UNDESIRED BITTER, ASTRINGENT IMPRESSION SYMRISE GMBH & CO. KG (DE) 2008-12-25 US claimed
EP-2001448-A2 FLAVOR-ENHANCING COMPOSITIONS, METHODS OF MANUFACTURE, AND METHODS OF USE Cadbury Adams USA LLC (US) 2008-12-17 EP claimed
US-20080214675-A1 Hydroxybenzoic Acid Amides and the Use Thereof For Masking Bitter Taste SYMRISE GMBH & CO. KG (DE) 2008-09-04 US claimed
WO-2007089652-A2 FLAVOR-ENHANCING COMPOSITIONS, METHODS OF MANUFACTURE, AND METHODS OF USE CADBURY ADAMS USA LLC (US) 2007-08-09 WO claimed
US-20070178123-A1 FLAVOR-ENHANCING COMPOSITIONS, METHOD OF MANUFACTURE, AND METHODS OF USE KRAFT FOODS GLOBAL BRANDS LLC 2007-08-02 US claimed
US-20250163006-A1 New Coolants, and Preparations Containing Same SYMRISE AG (DE) 2025-05-22 US disclosed
US-20250066320-A1 Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same SYMRISE AG (DE) 2025-02-27 US disclosed
EP-3689324-B1 NEW COOLING AGENTS AND PREPARATIONS COMPRISING THEM SYMRISE AG (DE) 2024-11-20 EP disclosed
EP-4452941-A1 ACTIVE INGREDIENTS WITH SIALAGOGUE AND TINGLING/FIZZY EFFECT, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2024-10-30 EP disclosed
EP-1909599-A1 USE OF HESPERETIN FOR ENHANCING THE SWEET TASTE Symrise GmbH & Co. KG (DE) 2008-04-16 EP disclosed
WO-2007107596-A1 USE OF 4-HYDROXYDIHYDROCHALCONES AND THEIR SALTS FOR ENHANCING AN IMPRESSION OF SWEETNESS SYMRISE GMBH & CO. KG (DE) 2007-09-27 WO disclosed
WO-2007089652-A2 FLAVOR-ENHANCING COMPOSITIONS, METHODS OF MANUFACTURE, AND METHODS OF USE CADBURY ADAMS USA LLC (US) 2007-08-09 WO disclosed
US-20070178123-A1 FLAVOR-ENHANCING COMPOSITIONS, METHOD OF MANUFACTURE, AND METHODS OF USE KRAFT FOODS GLOBAL BRANDS LLC 2007-08-02 US disclosed
WO-2007014879-A1 USE OF HESPERETIN FOR ENHANCING THE SWEET TASTE SYMRISE GMBH & CO. KG (DE) 2007-02-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250066320-A1 Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same TAS2R5, TAS2R7, TAS2R8 ALOX15 287/4885ALPL 677/4885ERCC1 4799/4885
US-20250163006-A1 New Coolants, and Preparations Containing Same TTR, TAS2R5, TAS2R50 ALOX15 2738/4885ALPL 1347/4885ERCC1 1867/4885
US-20190289886-A1 SUBSTANCE MIXTURES PNN, NISCH, HES1 ALOX15 4177/4885ALPL 3061/4885ERCC1 3429/4885
US-20080214675-A1 Hydroxybenzoic Acid Amides and the Use Thereof For Masking Bitter Taste TAS1R1, TAS2R1, TAS1R2 ALOX15 426/4885ALPL 4820/4885ERCC1 1378/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.