Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.54 |
| ▸ | KLK7 | P49862 | 1/20 | 0.52 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 4/20 | 0.51 |
| ▸ | PPARG | P37231 | 4/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 4/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10887447 | 0.92 | PPARA (0.53) | PPARAKLK7KLK5CTSSPPARG | |
| SCHEMBL11599337 | 0.92 | PPARA (0.53) | PPARAKLK7KLK5CTSSPPARG | |
| SCHEMBL14997847 | 0.92 | PPARA (0.53) | PPARAKLK7KLK5CTSSPPARG | |
| SCHEMBL3817109 | 0.92 | PPARA (0.55) | PPARAKLK7KLK5CTSSPPARG | |
| SCHEMBL13007476 | 0.92 | PPARA (0.55) | PPARAKLK7KLK5CTSSPPARG | |
| SCHEMBL2011835 | 0.92 | PPARA (0.55) | PPARAKLK7KLK5CTSSPPARG | |
| SCHEMBL1517760 | 0.92 | PPARA (0.55) | PPARAKLK7KLK5CTSSPPARG | |
| SCHEMBL376018 | 0.92 | PPARA (0.61) | PPARAKLK7KLK5CTSSPPARG | |
| SCHEMBL2009896 | 0.92 | PPARA (0.61) | PPARAKLK7KLK5CTSSPPARG | |
| SCHEMBL428113 | 0.92 | PPARA (0.61) | PPARAKLK7KLK5CTSSPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188119-B2 | Pyridine derivatives substituted with heterocyclic ring and γ-glutamylamino group, and antifungal agents containing same | EISAI R&D MANAGEMENT CO., LTD (JP) | 2012-05-29 | — | — | US | disclosed |
| US-8034898-B2 | Methods of collagen imaging | Collagen Medical, LLC (US) | 2011-10-11 | — | — | US | disclosed |
| US-20100105737-A1 | PYRIDINE DERIVATIVES SUBSTITUTED WITH HETEROCYCLIC RING AND gamma-GLUTAMYLAMINO GROUP, AND ANTIFUNGAL AGENTS CONTAINING SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-04-29 | — | — | US | disclosed |
| US-20080058636-A1 | METHODS OF MYOCARDIAL IMAGING | EPIX PHARMACEUTICALS, INC. | 2008-03-06 | — | — | US | disclosed |
| US-20080044360-A1 | METHODS OF COLLAGEN IMAGING | EPIX PHARMACEUTICALS, INC. | 2008-02-21 | — | — | US | disclosed |
| US-20070293656-A1 | COLLAGEN BINDING PEPTIDES | EPIX PHARMACEUTICALS, INC. | 2007-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105737-A1 | PYRIDINE DERIVATIVES SUBSTITUTED WITH HETEROCYCLIC RING AND gamma-GLUTAMYLAMINO GROUP, AND ANTIFUNGAL AGENTS CONTAINING SAME | ASNS, ERG28, GLUL | PPARA 4236/4885KLK7 4126/4885KLK5 4350/4885 |
| US-20080058636-A1 | METHODS OF MYOCARDIAL IMAGING | FABP3, TNNI3, TNNT2 | PPARA 1968/4885KLK7 998/4885KLK5 1079/4885 |
| US-20080044360-A1 | METHODS OF COLLAGEN IMAGING | COL14A1, COL2A1, COL1A1 | PPARA 2334/4885KLK7 271/4885KLK5 718/4885 |
| US-20070293656-A1 | COLLAGEN BINDING PEPTIDES | COL14A1, COL2A1, COL1A1 | PPARA 2643/4885KLK7 1044/4885KLK5 1541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.