Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.37 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 2/20 | 0.36 |
| ▸ | CCND1 | P24385 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | HNF4A | P41235 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4256764 | 0.74 | ALDH1A1 (0.41) | ALDH1A1HSD17B10HPGDBCL2L1BACE1 | |
| SCHEMBL8984765 | 0.72 | ALDH1A1 (0.39) | ALDH1A1HSD17B10HPGDBCL2L1BACE1 | |
| SCHEMBL3401845 | 0.71 | THRB (0.50) | ALDH1A1HSD17B10HPGDBCL2L1BACE1 | |
| SCHEMBL30741411 | 0.71 | THRB (0.50) | ALDH1A1HSD17B10HPGDBCL2L1BACE1 | |
| SCHEMBL25818400 | 0.70 | THRB (0.43) | ALDH1A1HSD17B10HPGDBCL2L1BACE1 | |
| SCHEMBL30084636 | 0.67 | ALDH1A1 (0.41) | ALDH1A1HSD17B10HPGDBCL2L1BACE1 | |
| SCHEMBL706442 | 0.67 | ALDH1A1 (0.41) | ALDH1A1HSD17B10HPGDBCL2L1BACE1 | |
| SCHEMBL28437143 | 0.67 | PDK2 (0.42) | ALDH1A1HSD17B10HPGDBCL2L1TDP1 | |
| SCHEMBL27643267 | 0.67 | THRB (0.46) | ALDH1A1HSD17B10HPGDBCL2L1BACE1 | |
| SCHEMBL27497315 | 0.67 | THRB (0.71) | ALDH1A1HSD17B10HPGDBCL2L1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578737-A | SUBSTITUTED FLUORENES, MONOMERS FOR HIGH PERFORMANCE POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1996-11-26 | — | — | US | disclosed |
| US-5387725-A | Chlorinating compounds having acidic protons with a perchloro-alkane and aqueous base in the presence of a tetraalkyl-ammonium hydroxide phase transfer catalyst | THE DOW CHEMICAL COMPANY (US) | 1995-02-07 | — | — | US | disclosed |
| EP-0611366-A1 | CHLORINATION PROCESS, ALKYLATION OF PRODUCTS OF SAID PROCESS AND SOME PRODUCTS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1994-08-24 | — | — | EP | disclosed |
| WO-1993009074-A2 | CHLORINATION PROCESS, ALKYLATION OF PRODUCTS OF SAID PROCESS AND SOME PRODUCTS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1993-05-13 | — | — | WO | disclosed |