Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 3/20 | 0.31 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7293488 | 0.80 | CA2 (0.39) | GPR84FFAR1LTB4R | |
| SCHEMBL8985079 | 0.79 | GPR84 (0.32) | LCKPPARDZDHHC20ZDHHC2GPR84 | |
| SCHEMBL8985039 | 0.79 | GPR84 (0.32) | LCKPPARDZDHHC20ZDHHC2GPR84 | |
| SCHEMBL9744651 | 0.78 | ALDH1A1 (0.32) | MAPT | |
| SCHEMBL7326578 | 0.78 | ALDH1A1 (0.38) | LTB4R | |
| SCHEMBL9803456 | 0.77 | GLS2 (0.34) | LTB4R | |
| SCHEMBL9766908 | 0.77 | ZDHHC7 (0.43) | — | |
| SCHEMBL9677956 | 0.76 | — | — | |
| SCHEMBL9160196 | 0.76 | FAAH (0.35) | MAPTALDH2 | |
| SCHEMBL9128899 | 0.75 | LMNA (0.38) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541221-A | Pharmaceutical compositions and method for administering 3 and 4-substituted 2(5H)-furanones to a mammal for inhibiting bone loss | ALLERGAN (US) | 1996-07-30 | — | — | US | disclosed |