Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.30 |
| ▸ | UBE2N | P61088 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985493 | 0.85 | PTGS1 (0.41) | PTGS1PTGS2ALDH1A1L3MBTL1NOX1 | |
| SCHEMBL8985338 | 0.82 | MAPK14 (0.46) | PTGS1PTGS2L3MBTL1NOX1UBE2N | |
| SCHEMBL8985322 | 0.82 | PTGS2 (0.33) | PTGS1PTGS2 | |
| SCHEMBL8985449 | 0.81 | OPRD1 (0.38) | PTGS1PTGS2L3MBTL1NOX1UBE2N | |
| SCHEMBL8985529 | 0.81 | — | — | |
| SCHEMBL8985365 | 0.79 | PTGS1 (0.35) | PTGS1PTGS2ALDH1A1L3MBTL1UBE2N | |
| SCHEMBL8985294 | 0.77 | PTGS1 (0.40) | PTGS1PTGS2ALDH1A1L3MBTL1UBE2N | |
| SCHEMBL8985530 | 0.77 | MAPK14 (0.52) | PTGS1PTGS2ALDH1A1L3MBTL1UBE2N | |
| SCHEMBL8585909 | 0.76 | ALDH1A1 (0.50) | ALDH1A1NOX1 | |
| SCHEMBL8985459 | 0.76 | CYP1A2 (0.37) | PTGS1PTGS2ALDH1A1L3MBTL1UBE2N |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |