Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.61 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.48 |
| ▸ | EP300 | Q09472 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985478 | 0.83 | MAPK14 (0.48) | OPRD1MAPK14EP300PTGS2PTGS1 | |
| SCHEMBL8985383 | 0.82 | MAPK14 (0.70) | OPRD1MAPK14EP300BACE1PTGS2 | |
| SCHEMBL8985453 | 0.81 | OPRD1 (0.62) | OPRD1MAPK14EP300PTGS2PTGS1 | |
| SCHEMBL8985533 | 0.80 | OPRD1 (0.64) | OPRD1MAPK14EP300BACE1PTGS2 | |
| SCHEMBL8985255 | 0.79 | MAPK14 (0.45) | OPRD1MAPK14PTGS2PTGS1 | |
| SCHEMBL8985252 | 0.78 | MAPK14 (0.44) | OPRD1MAPK14EP300PTGS2PTGS1 | |
| SCHEMBL7899259 | 0.77 | OPRD1 (0.81) | OPRD1MAPK14EP300BACE1PTGS2 | |
| SCHEMBL7619448 | 0.77 | PTGS2 (0.68) | OPRD1MAPK14PTGS2PTGS1KDM4E | |
| SCHEMBL8985511 | 0.74 | OPRD1 (0.74) | OPRD1EP300BACE1PTGS2PTGS1 | |
| SCHEMBL8985468 | 0.74 | OPRD1 (0.70) | OPRD1MAPK14EP300BACE1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |