Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8988515 | 0.93 | HRH3 (0.36) | ALDH1A1LMNATDP1L3MBTL1HRH3 | |
| SCHEMBL8988493 | 0.90 | CYP4F2 (0.38) | LMNAL3MBTL1CYP4F2CYP4A11HRH3 | |
| Hydrochloric Acid SCHEMBL8988681 | 0.89 | ITGB3 (0.40) | ALDH1A1LMNATDP1L3MBTL1CYP4F2 | |
| SCHEMBL9564733 | 0.88 | HRH3 (0.32) | ALDH1A1LMNATDP1L3MBTL1HRH3 | |
| SCHEMBL9564737 | 0.87 | HRH3 (0.34) | ALDH1A1LMNATDP1L3MBTL1CYP4F2 | |
| Bicarbonate SCHEMBL8988879 | 0.86 | PTPN1 (0.33) | ALDH1A1LMNATDP1L3MBTL1HRH3 | |
| SCHEMBL9564731 | 0.86 | CASP1 (0.33) | HRH3HDAC1PTPN1 | |
| SCHEMBL9564728 | 0.85 | HRH3 (0.33) | HRH3HDAC1PTPN1 | |
| SCHEMBL8988601 | 0.84 | ALDH1A1 (0.30) | ALDH1A1LMNATDP1L3MBTL1FAAH | |
| Hydrochloric Acid SCHEMBL8988806 | 0.84 | HRH3 (0.36) | LMNAL3MBTL1HRH3HDAC1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489693-A | ANTICOAGULANTS | DR. KARK THOMAE, GMBH (DE) | 1996-02-06 | — | — | US | disclosed |
| EP-0567968-A1 | Cyclic imino derivatives, medicaments containing these compounds and processes for the production thereof | Dr. Karl Thomae GmbH (DE) | 1993-11-03 | — | — | EP | disclosed |