Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 4/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MASP2 | O00187 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8988708 | 0.96 | MASP2 (0.32) | HRH3PTPN1HDAC1KLKB1CYP4F2 | |
| SCHEMBL8988493 | 0.94 | CYP4F2 (0.38) | HRH3PTPN1CYP4F2CYP4A11CASP3 | |
| SCHEMBL8988515 | 0.94 | HRH3 (0.36) | HRH3PTPN1HDAC1ITGB3ITGA2B | |
| SCHEMBL9564728 | 0.91 | HRH3 (0.33) | HRH3PTPN1HDAC1 | |
| SCHEMBL9564731 | 0.90 | CASP1 (0.33) | HRH3PTPN1HDAC1 | |
| SCHEMBL8988692 | 0.87 | CASP1 (0.32) | HRH3PTPN1HDAC1 | |
| SCHEMBL8988712 | 0.87 | ALDH1A1 (0.35) | HRH3PTPN1HDAC1CYP4F2CYP4A11 | |
| SCHEMBL9564733 | 0.87 | HRH3 (0.32) | HRH3PTPN1HDAC1LMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8988806 | 0.87 | HRH3 (0.36) | HRH3PTPN1HDAC1ITGB3ITGA2B | |
| Bicarbonate SCHEMBL8988879 | 0.85 | PTPN1 (0.33) | HRH3PTPN1HDAC1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567968-A1 | Cyclic imino derivatives, medicaments containing these compounds and processes for the production thereof | Dr. Karl Thomae GmbH (DE) | 1993-11-03 | — | — | EP | disclosed |