Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564737 | 0.94 | HRH3 (0.34) | HRH3PTPN1HDAC1LMNAL3MBTL1 | |
| SCHEMBL8988493 | 0.93 | CYP4F2 (0.38) | HRH3PTPN1LMNAL3MBTL1ITGB3 | |
| SCHEMBL8988712 | 0.93 | ALDH1A1 (0.35) | HRH3PTPN1HDAC1TP53LMNA | |
| SCHEMBL9564728 | 0.92 | HRH3 (0.33) | HRH3PTPN1HDAC1 | |
| SCHEMBL9564731 | 0.91 | CASP1 (0.33) | HRH3PTPN1HDAC1 | |
| SCHEMBL9564733 | 0.91 | HRH3 (0.32) | HRH3PTPN1HDAC1LMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8988806 | 0.91 | HRH3 (0.36) | HRH3PTPN1HDAC1TP53LMNA | |
| SCHEMBL8988708 | 0.90 | MASP2 (0.32) | HRH3PTPN1HDAC1ITGB3ITGA2B | |
| Bicarbonate SCHEMBL8988879 | 0.89 | PTPN1 (0.33) | HRH3PTPN1HDAC1LMNAL3MBTL1 | |
| SCHEMBL8988689 | 0.89 | ITGB3 (0.43) | HRH3PTPN1HDAC1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489693-A | ANTICOAGULANTS | DR. KARK THOMAE, GMBH (DE) | 1996-02-06 | — | — | US | disclosed |
| EP-0567968-A1 | Cyclic imino derivatives, medicaments containing these compounds and processes for the production thereof | Dr. Karl Thomae GmbH (DE) | 1993-11-03 | — | — | EP | disclosed |