Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8988635 | 0.99 | ITGB3 (0.34) | ITGB3ITGA2BCASP1CSNK2A2CSNK2A1 | |
| SCHEMBL9564731 | 0.94 | CASP1 (0.33) | CASP1CSNK2A2CSNK2A1 | |
| SCHEMBL8988692 | 0.91 | CASP1 (0.32) | CASP1 | |
| SCHEMBL8988621 | 0.88 | CASP1 (0.32) | CASP1 | |
| SCHEMBL8988616 | 0.88 | CASP1 (0.35) | CASP1MAPT | |
| SCHEMBL8988601 | 0.86 | ALDH1A1 (0.30) | FAAHALDH1A1 | |
| SCHEMBL9564740 | 0.85 | FKBP1A (0.36) | CASP1ALDH1A1POLBMAPT | |
| SCHEMBL8988515 | 0.84 | HRH3 (0.36) | ITGB3ITGA2BALDH1A1POLBMAPT | |
| Hydrochloric Acid SCHEMBL8988917 | 0.84 | ITGB3 (0.40) | ITGB3ITGA2BPPARDPPARAMAPT | |
| SCHEMBL9564737 | 0.83 | HRH3 (0.34) | ITGB3ITGA2BALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489693-A | ANTICOAGULANTS | DR. KARK THOMAE, GMBH (DE) | 1996-02-06 | — | — | US | disclosed |
| EP-0567968-A1 | Cyclic imino derivatives, medicaments containing these compounds and processes for the production thereof | Dr. Karl Thomae GmbH (DE) | 1993-11-03 | — | — | EP | disclosed |