Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991057 | 0.92 | GHSR (0.40) | AGTR1GHSRHDAC1HDAC7SIGMAR1 | |
| SCHEMBL8990788 | 0.85 | GHSR (0.47) | AGTR1GHSRSIGMAR1 | |
| SCHEMBL8990938 | 0.84 | GHSR (0.48) | AGTR1GHSRSIGMAR1 | |
| SCHEMBL8990793 | 0.83 | GHSR (0.38) | AGTR1GHSRHDAC1SIGMAR1KMT2A | |
| SCHEMBL8990823 | 0.82 | AGTR1 (0.42) | AGTR1GHSRSIGMAR1 | |
| SCHEMBL8990845 | 0.81 | GHSR (0.37) | AGTR1GHSRHDAC1SIGMAR1KMT2A | |
| SCHEMBL8990949 | 0.78 | GHSR (0.43) | AGTR1GHSRKMT2A | |
| SCHEMBL8990747 | 0.77 | GHSR (0.36) | AGTR1GHSR | |
| SCHEMBL8991052 | 0.77 | — | — | |
| SCHEMBL8990891 | 0.76 | GHSR (0.36) | AGTR1GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |