Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991489 | 0.87 | MTNR1A (0.43) | LMNAPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8991519 | 0.79 | GAA (0.44) | GAAHTR1ADRD2BCHEPTGER1 | |
| SCHEMBL28375679 | 0.77 | HTR1A (0.65) | GAAHTR1ADRD2BCHEPTGER1 | |
| SCHEMBL10956404 | 0.77 | HTR1A (0.65) | GAAHTR1ADRD2BCHEPTGER1 | |
| SCHEMBL21483728 | 0.72 | HTR1A (0.57) | GAAHTR1ADRD2LIPELMNA | |
| SCHEMBL12745448 | 0.72 | HTR1A (0.59) | HTR1ALIPELMNAMAPTTDP1 | |
| SCHEMBL1690480 | 0.72 | HTR1A (0.61) | GAAHTR1ADRD2LIPELMNA | |
| SCHEMBL20507263 | 0.71 | TNNC1 (0.49) | LMNAKDM4EALDH1A1TP53 | |
| SCHEMBL1614610 | 0.71 | RXRA (0.43) | LIPEBCHEMAPTTDP1L3MBTL1 | |
| SCHEMBL1614851 | 0.71 | RXRA (0.43) | LIPEBCHEMAPTTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516227-B1 | Dry analytical element for lithium assay | JOHNSON & JOHNSON CLIN DIAG (US) | 1996-07-24 | — | — | EP | disclosed |
| US-5245021-A | Lithium carbonate analysis | EASTMAN KODAK COMPANY (US) | 1993-09-14 | — | — | US | disclosed |
| US-5188802-A | Containing dye derivative of 14-crown-4 ether; colorimetric analysis | EASTMAN KODAK COMPANY (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0516227-A2 | Dry analytical element for lithium assay | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-12-02 | — | — | EP | disclosed |
| EP-0516226-A1 | Novel 14-crown-4-ether derivatives | EASTMAN KODAK COMPANY (US) | 1992-12-02 | — | — | EP | disclosed |