Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.54 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917105 | 0.74 | DRD2 (0.54) | HTR1ADRD4DRD2ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL8917302 | 0.73 | ALDH1A1 (0.52) | HTR1ADRD4DRD2ALDH1A1POLB | |
| SCHEMBL3188003 | 0.71 | ALDH1A1 (0.71) | HTR1ADRD4DRD2ALDH1A1POLB | |
| SCHEMBL1491175 | 0.71 | HTR1A (0.71) | HTR1ADRD4DRD2ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL6601969 | 0.70 | HTR1A (0.98) | HTR1ADRD4DRD2ALDH1A1DRD3 | |
| Hydrochloric Acid SCHEMBL3196115 | 0.70 | HTR1A (0.71) | HTR1ADRD4DRD2ALDH1A1POLB | |
| SCHEMBL9037998 | 0.70 | DRD3 (0.61) | HTR1ADRD4DRD2ALDH1A1HTR7 | |
| SCHEMBL8916897 | 0.70 | HTR1A (0.59) | HTR1ADRD4DRD2ALDH1A1POLB | |
| Fluanisone SCHEMBL145054 | 0.70 | ALDH1A1 (1.00) | HTR1ADRD4DRD2ALDH1A1POLB | |
| Oxalic Acid SCHEMBL9042871 | 0.70 | DRD3 (0.59) | HTR1ADRD4DRD2ALDH1A1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0596125-A1 | CONDENSED THIOPHENE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |