Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TK1 | P04183 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9296625 | 0.84 | ALDH1A1 (0.44) | CYP3A4NPSR1ALDH1A1HSD17B10CHRM2 | |
| SCHEMBL11598437 | 0.83 | CYP2C19 (0.44) | CYP3A4NPSR1ALDH1A1HSD17B10CHRM2 | |
| SCHEMBL9230354 | 0.82 | CYP3A4 (0.55) | CYP3A4TK1NPSR1L3MBTL1ALDH1A1 | |
| SCHEMBL3541681 | 0.80 | MEN1 (0.49) | CYP3A4L3MBTL1ALDH1A1CHRM2CHRM4 | |
| SCHEMBL27880966 | 0.76 | NPSR1 (0.44) | CYP3A4MAPTNPSR1ALDH1A1HSD17B10 | |
| P-Xylene SCHEMBL11403520 | 0.75 | CYP3A4 (0.46) | CYP3A4MAPTNPSR1L3MBTL1ALDH1A1 | |
| SCHEMBL9270334 | 0.75 | SNCA (0.58) | CYP3A4MAPTALDH1A1HSD17B10TSHR | |
| SCHEMBL7724618 | 0.74 | MAPT (0.38) | CYP3A4MAPTNPSR1ALDH1A1HSD17B10 | |
| SCHEMBL5084136 | 0.74 | LMNA (0.55) | CYP3A4L3MBTL1ALDH1A1CHRM2CHRM4 | |
| SCHEMBL5282428 | 0.74 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1CNR1CNR2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445749-B1 | N-Monosubstituted cyclopentenylamines, a process for their preparation and their use as medicaments | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5256824-A | Anticholinergic agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-26 | — | — | US | disclosed |
| EP-0445749-A1 | N-Monosubstituted cyclopentenylamines, a process for their preparation and their use as medicaments | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-11 | — | — | EP | disclosed |