Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7724597 | 0.82 | ALDH1A1 (0.35) | MAPTADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL7725794 | 0.81 | L3MBTL1 (0.38) | TP53MEN1KMT2ATDP1 | |
| SCHEMBL7724398 | 0.79 | ALDH1A1 (0.41) | MAPTALDH1A1POLBKDM4EKMT2A | |
| SCHEMBL7724591 | 0.76 | ALOX5 (0.38) | ALDH1A1TP53MEN1KMT2A | |
| SCHEMBL7730011 | 0.75 | ATM (0.50) | ALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL8992390 | 0.74 | CYP3A4 (0.43) | MAPTCYP3A4ALDH1A1NPSR1HSD17B10 | |
| SCHEMBL7730042 | 0.74 | MMP2 (0.38) | MEN1KMT2ATSHR | |
| SCHEMBL7725820 | 0.74 | TSPO (0.37) | ALDH1A1 | |
| SCHEMBL7724611 | 0.72 | MMP13 (0.40) | CYP3A4TP53TSHR | |
| SCHEMBL7720010 | 0.72 | PKM (0.42) | ALDH1A1HSD17B10KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403818-B1 | ONE POT PROCESS STARTING FROM CARBONYL COMPOUND, ALCOHOL, THIOL OR AMINE, AND PROTECTED HYDROXYDICYANO COMPOUND | EISAI CO., LTD. (JP) | 2002-06-11 | — | — | US | disclosed |