Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219561 | 0.92 | RAB9A (0.52) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8993403 | 0.88 | RAB9A (0.44) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8992955 | 0.88 | NPC1 (0.43) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8992965 | 0.87 | GPR119 (0.41) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8992990 | 0.84 | KMT2A (0.48) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9215696 | 0.82 | RAB9A (0.42) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8992922 | 0.81 | GPR119 (0.43) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL8993148 | 0.81 | KMT2A (0.41) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL8993290 | 0.80 | GPR119 (0.41) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9215756 | 0.80 | SRC (0.45) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |