Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993260 | 0.85 | TTR (0.50) | MEN1LMNAPOLBKMT2ACNR2 | |
| SCHEMBL8992924 | 0.83 | CNR2 (0.45) | MEN1POLBKMT2ACNR2GAA | |
| SCHEMBL8993391 | 0.81 | CNR2 (0.44) | MEN1LMNAPOLBKMT2ACNR2 | |
| SCHEMBL8993275 | 0.81 | CNR1 (0.44) | LMNACNR2TSHRCNR1PDCD1 | |
| SCHEMBL22800044 | 0.80 | CA2 (0.52) | CNR2GAAMAPTTSHRMAPK1 | |
| SCHEMBL8992814 | 0.80 | TUBB4A (0.47) | LMNACNR2GAAMAPTTSHR | |
| SCHEMBL3411267 | 0.79 | RAB9A (0.60) | MEN1LMNAPOLBKMT2AGAA | |
| SCHEMBL20200250 | 0.78 | PDCD1 (0.51) | POLBGAAMAPTTSHRMAPK1 | |
| SCHEMBL31280574 | 0.78 | PDCD1 (0.51) | POLBGAAMAPTTSHRMAPK1 | |
| SCHEMBL8035410 | 0.78 | CNR2 (0.55) | CNR2GAAMAPTGPR55CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |