Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 4/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993322 | 0.84 | CNR2 (0.45) | CNR2GPR55GAAMAPTTSHR | |
| SCHEMBL8993099 | 0.82 | CNR2 (0.44) | CNR2CNR1TSHRLMNA | |
| SCHEMBL8992888 | 0.81 | MEN1 (0.44) | CNR2GPR55CNR1GAAMAPT | |
| SCHEMBL8993260 | 0.81 | TTR (0.50) | CNR2GPR55CNR1GAAMAPT | |
| SCHEMBL8992887 | 0.81 | TUBB4A (0.44) | CNR2GAAMAPTTSHRMAPK1 | |
| SCHEMBL8993396 | 0.80 | CNR2 (0.48) | CNR2GPR55CNR1MEN1KMT2A | |
| SCHEMBL8992952 | 0.79 | NPC1 (0.50) | HTR7GAAMAPTTSHRNPC1 | |
| SCHEMBL8993373 | 0.78 | LTA4H (0.43) | MAPTTSHRMEN1LMNAKMT2A | |
| SCHEMBL22800044 | 0.77 | CA2 (0.52) | CNR2GAAMAPTTSHRMAPK1 | |
| SCHEMBL1008180 | 0.77 | HTR7 (0.43) | HTR7GAAMAPTTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |