Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL108109 | 0.76 | TAAR1 (0.62) | ALDH1A1TAAR1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8993116 | 0.75 | LTA4H (0.45) | MPOLTB4RCYP3A4CYP2D6 | |
| SCHEMBL109195 | 0.74 | TAAR1 (0.64) | ALDH1A1TAAR1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8992834 | 0.73 | LTA4H (0.53) | MPOALDH1A1TAAR1CYP3A4CHEK2 | |
| SCHEMBL9036923 | 0.72 | PTGS2 (0.51) | ALDH1A1TAAR1SLC6A4CYP3A4 | |
| SCHEMBL8993151 | 0.72 | CYP3A4 (0.57) | ALDH1A1TAAR1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8992951 | 0.71 | LTA4H (0.57) | LTB4RTAAR1ADORA1 | |
| SCHEMBL8993059 | 0.70 | CHEK2 (0.43) | ALDH1A1HSD17B10LTB4RCYP3A4CHEK2 | |
| SCHEMBL1422874 | 0.70 | ALDH1A1 (0.58) | ALDH1A1TAAR1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL15599268 | 0.69 | LTB4R (0.50) | MPOALDH1A1HSD17B10LTB4RTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |