Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095627 | 0.89 | LTA4H (0.53) | TSHRLTA4HKEAP1TAAR1FFAR1 | |
| SCHEMBL9144897 | 0.83 | TDP1 (0.52) | LTA4HKEAP1TAAR1FFAR1 | |
| SCHEMBL3926343 | 0.83 | KEAP1 (0.67) | LTA4HKEAP1TAAR1 | |
| SCHEMBL2140995 | 0.82 | CALM1 (0.57) | TSHRLTA4HKEAP1TAAR1FFAR1 | |
| SCHEMBL6378299 | 0.82 | POLB (0.51) | TSHRLTA4HKEAP1TAAR1FFAR1 | |
| SCHEMBL11150868 | 0.82 | TSHR (0.52) | TSHRLTA4HKEAP1 | |
| SCHEMBL29940610 | 0.81 | CALM1 (0.55) | TSHRLTA4HTAAR1 | |
| SCHEMBL275838 | 0.81 | CALM1 (0.55) | TSHRLTA4HTAAR1 | |
| SCHEMBL9741301 | 0.81 | CALM1 (0.55) | TSHRLTA4HTAAR1 | |
| SCHEMBL8993189 | 0.80 | BCL2 (0.47) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1735408-A | Receptor function controlling agent | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2006-02-15 | — | — | CN | disclosed |
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |