Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28414146 | 0.88 | MTNR1B (0.59) | MTNR1AMTNR1BSMN1; SMN2NPC1MEN1 | |
| SCHEMBL5213132 | 0.87 | LOXL2 (0.71) | SMN1; SMN2NPC1RAB9APOLBBLM | |
| SCHEMBL1897614 | 0.85 | CA1 (0.59) | SMN1; SMN2NPC1RAB9APOLBBLM | |
| Hydrochloric Acid SCHEMBL16506765 | 0.84 | HDAC1 (0.74) | SMN1; SMN2NPC1RAB9APOLBBLM | |
| SCHEMBL8993003 | 0.84 | CA1 (0.78) | SMN1; SMN2NPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL9607150 | 0.84 | MTNR1A (0.59) | MTNR1AMTNR1BNPC1RAB9AKMT2A | |
| SCHEMBL10069983 | 0.84 | NPC1 (0.60) | MTNR1AMTNR1BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8993120 | 0.83 | MAPT (0.56) | SMN1; SMN2RAB9AMEN1KMT2ATP53 | |
| SCHEMBL481113 | 0.83 | LOXL2 (0.56) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL3646136 | 0.82 | RAB9A (0.65) | SMN1; SMN2NPC1RAB9APOLBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |