SCHEMBL1680744

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1680499	0.83	TAAR1 (0.40)	TAAR1KMT2AMEN1CHRM2CARM1
	SCHEMBL1680943	0.82	LTA4H (0.38)	NPC1RAB9ALMNAHPGD
	Ammonia Solution, Strong SCHEMBL28621254	0.79	NPC1 (0.37)	NPC1RAB9ATAAR1LMNAPNMT
	SCHEMBL17398402	0.79	NPC1 (0.38)	NPC1RAB9ATAAR1LMNAPNMT
	SCHEMBL8993057	0.75	LTA4H (0.43)	NPC1RAB9ATAAR1PNMTSIGMAR1
	SCHEMBL1680485	0.73	ALOX5 (0.36)	TAAR1LMNAKMT2AMEN1OPRK1
	SCHEMBL1680796	0.72	PNMT (0.39)	NPC1RAB9ATAAR1PNMTSIGMAR1
	SCHEMBL17398586	0.72	NPC1 (0.40)	NPC1RAB9ALMNAKMT2AMEN1
	SCHEMBL17398494	0.72	RXFP1 (0.37)	NPC1RAB9AMAPTKDM4EHTT
	SCHEMBL1680462	0.72	PNMT (0.58)	TAAR1LMNAPNMTMAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.