SCHEMBL1680796

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1680459	0.84	ATM (0.41)	TAAR1POLBIDO1AGXTDAO
	SCHEMBL1106846	0.83	CALM1 (0.37)	NPC1RAB9A
	SCHEMBL8993057	0.76	LTA4H (0.43)	PNMTTAAR1SIGMAR1NPC1RAB9A
	SCHEMBL510447	0.74	LMNA (0.33)	TAAR1POLBNPC1IDO1
	SCHEMBL1680744	0.72	NPC1 (0.42)	PNMTTAAR1SIGMAR1NPC1RAB9A
	Ammonia Solution, Strong SCHEMBL28621254	0.71	NPC1 (0.37)	PNMTTAAR1SIGMAR1NPC1RAB9A
	SCHEMBL1680672	0.71	PNMT (0.60)	PNMTTAAR1CYP3A4IDO1AGXT
	SCHEMBL4485406	0.71	TAAR1 (0.51)	PNMTTAAR1CYP3A4IDO1AGXT
	SCHEMBL29910956	0.69	PNMT (0.47)	PNMTTAAR1GAASIGMAR1CYP3A4
	SCHEMBL3300276	0.69	PNMT (0.65)	PNMTTAAR1SIGMAR1CYP3A4IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.