Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KDR | P35968 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | BMP4 | P12644 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217924 | 0.92 | KMT2A (0.54) | KMT2ANPC1RAB9AKDRMAPT | |
| SCHEMBL8993148 | 0.92 | KMT2A (0.41) | KMT2ANPC1RAB9AKDRMAPT | |
| SCHEMBL8992950 | 0.89 | LTA4H (0.43) | KMT2ANPC1RAB9AMAPTLMNA | |
| SCHEMBL8993293 | 0.87 | KMT2A (0.40) | KMT2ANPC1RAB9AKDRMAPT | |
| SCHEMBL8992965 | 0.86 | GPR119 (0.41) | KMT2ANPC1RAB9AKDRMAPT | |
| SCHEMBL8992955 | 0.85 | NPC1 (0.43) | KMT2ANPC1RAB9AMAPTMEN1 | |
| SCHEMBL8993213 | 0.84 | RAB9A (0.46) | KMT2ANPC1RAB9AKDRMAPT | |
| SCHEMBL8992831 | 0.83 | LTA4H (0.42) | KMT2ANPC1RAB9AMAPTLMNA | |
| SCHEMBL9215696 | 0.82 | RAB9A (0.42) | KMT2ANPC1RAB9AKDRMAPT | |
| SCHEMBL8992922 | 0.80 | GPR119 (0.43) | KMT2ANPC1RAB9AKDRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |