Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 12/20 | 0.41 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993311 | 0.87 | POLB (0.43) | HPGDMAPTKDM4E | |
| SCHEMBL29519366 | 0.72 | PLA2G4A (0.45) | F11NHERF1HPGDMAPTPYGL | |
| SCHEMBL11953212 | 0.70 | NPC1 (0.65) | HPGDALOX15KDM4E | |
| SCHEMBL19628853 | 0.67 | RAB9A (0.49) | HPGDMAPTKDM4E | |
| SCHEMBL8993354 | 0.67 | POLB (0.44) | MAPT | |
| SCHEMBL14614384 | 0.66 | KDM4E (0.44) | F11KLKB1KDM4E | |
| SCHEMBL9335595 | 0.65 | HPGD (0.67) | HPGDALOX15MAPTKDM4E | |
| SCHEMBL6379411 | 0.65 | MAPT (0.58) | HPGDALOX15MAPT | |
| SCHEMBL3001175 | 0.63 | SMN1; SMN2 (0.64) | HPGDMAPT | |
| SCHEMBL11466437 | 0.63 | MEN1 (0.81) | HPGDMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519043-A | ANTIINFLAMMATORY AGENTS WITH AMIDE, CARBAMATE OR THIOCARBAMATE GROUPS ON FLUORENE AND BENZENE | SCIOS NOVA INC. (US) | 1996-05-21 | — | — | US | claimed |
| US-5519043-A | ANTIINFLAMMATORY AGENTS WITH AMIDE, CARBAMATE OR THIOCARBAMATE GROUPS ON FLUORENE AND BENZENE | SCIOS NOVA INC. (US) | 1996-05-21 | — | — | US | disclosed |