Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | PTGFR | P43088 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993273 | 0.87 | F11 (0.41) | KDM4EMAPTHPGD | |
| SCHEMBL8993354 | 0.81 | POLB (0.44) | POLBCA12CA1CA2CA9 | |
| SCHEMBL11953212 | 0.70 | NPC1 (0.65) | CA12CA2CA9KDM4EALDH1A1 | |
| SCHEMBL8993329 | 0.68 | NHERF1 (0.42) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL19628853 | 0.67 | RAB9A (0.49) | CA12CA2CA9KDM4EMAPT | |
| SCHEMBL19563255 | 0.64 | FPR2 (0.55) | POLBKDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL19563264 | 0.64 | FPR2 (0.55) | POLBKDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL3001175 | 0.63 | SMN1; SMN2 (0.64) | POLBCA1CA2MAPTALDH1A1 | |
| SCHEMBL16742520 | 0.62 | FPR2 (0.57) | MEN1KMT2ANPC1CYP1A2CYP2D6 | |
| SCHEMBL16742517 | 0.62 | FPR2 (0.57) | MEN1KMT2ANPC1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519043-A | ANTIINFLAMMATORY AGENTS WITH AMIDE, CARBAMATE OR THIOCARBAMATE GROUPS ON FLUORENE AND BENZENE | SCIOS NOVA INC. (US) | 1996-05-21 | — | — | US | disclosed |