Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | PTGFR | P43088 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993311 | 0.81 | POLB (0.43) | POLBSRD5A1SRD5A2CA12CA1 | |
| SCHEMBL8993273 | 0.67 | F11 (0.41) | MAPT | |
| SCHEMBL8993299 | 0.66 | EPHX2 (0.41) | POLBCA12CA2CA9KMT2A | |
| SCHEMBL16592202 | 0.64 | KMT2A (0.74) | POLBKMT2AMEN1MAPT | |
| SCHEMBL16583981 | 0.64 | KMT2A (0.74) | POLBKMT2AMEN1MAPT | |
| SCHEMBL3001175 | 0.64 | SMN1; SMN2 (0.64) | POLBCA1CA2KMT2AMEN1 | |
| SCHEMBL15937787 | 0.62 | CYP1A2 (0.50) | POLBSRD5A1SRD5A2KMT2AMEN1 | |
| SCHEMBL22075935 | 0.62 | MEN1 (0.62) | POLBKMT2AMEN1TDP1MAPT | |
| SCHEMBL24947713 | 0.62 | NAMPT (0.67) | — | |
| SCHEMBL29401210 | 0.62 | EPHX2 (0.63) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519043-A | ANTIINFLAMMATORY AGENTS WITH AMIDE, CARBAMATE OR THIOCARBAMATE GROUPS ON FLUORENE AND BENZENE | SCIOS NOVA INC. (US) | 1996-05-21 | — | — | US | claimed |
| US-5519043-A | ANTIINFLAMMATORY AGENTS WITH AMIDE, CARBAMATE OR THIOCARBAMATE GROUPS ON FLUORENE AND BENZENE | SCIOS NOVA INC. (US) | 1996-05-21 | — | — | US | disclosed |