Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993396 | 0.86 | CNR2 (0.48) | CNR2CNR1 | |
| SCHEMBL8993322 | 0.86 | CNR2 (0.45) | CNR2LMNATSHRSMN1; SMN2CA2 | |
| SCHEMBL8992798 | 0.83 | ENPP2 (0.41) | CNR2CNR1ENPP2 | |
| SCHEMBL8993391 | 0.82 | CNR2 (0.44) | CNR2CNR1LMNATSHR | |
| SCHEMBL8993275 | 0.82 | CNR1 (0.44) | CNR2CNR1LMNATP53HPGD | |
| SCHEMBL8992887 | 0.80 | TUBB4A (0.44) | CNR2TSHRCA2ALDH1A1 | |
| SCHEMBL625612 | 0.79 | ENPP2 (0.53) | LMNAMAOBENPP2 | |
| SCHEMBL8992963 | 0.78 | LTA4H (0.46) | TP53ENPP2 | |
| SCHEMBL8992807 | 0.76 | CNR2 (0.46) | CNR2CNR1MAOB | |
| SCHEMBL6228438 | 0.75 | PIK3CD (0.41) | TSHRCA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516777-A | PROSTATE CANCER THERAPY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5409928-A | Prostate diseases, alopecia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0594149-A2 | Condensed pyrazole derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |