Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.67 |
| ▸ | BLM | P54132 | 3/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | APEX1 | P27695 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7927945 | 0.85 | NFKB1 (0.62) | NFKB1BLMPMP22ADRA2AADRA1A | |
| SCHEMBL7927950 | 0.85 | NFKB1 (0.62) | NFKB1BLMPMP22ADRA2AADRA1A | |
| SCHEMBL15241060 | 0.84 | CYP3A4 (0.49) | NFKB1BLMPMP22CYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL7930046 | 0.83 | BLM (0.63) | NFKB1BLMPMP22ADRA2AADRA1A | |
| SCHEMBL15240924 | 0.82 | CYP3A4 (0.66) | NFKB1BLMPMP22CYP3A4TSHR | |
| Normetanephrine SCHEMBL4949341 | 0.80 | NFKB1 (1.00) | NFKB1BLMPMP22ADRA2AADRA1A | |
| Normetanephrine SCHEMBL29516838 | 0.80 | NFKB1 (1.00) | NFKB1BLMPMP22ADRA2AADRA1A | |
| Normetanephrine SCHEMBL137755 | 0.80 | NFKB1 (1.00) | NFKB1BLMPMP22ADRA2AADRA1A | |
| SCHEMBL15921910 | 0.79 | NFKB1 (0.75) | NFKB1BLMPMP22ADRA2AADRA1A | |
| SCHEMBL15240656 | 0.79 | CYP3A4 (0.49) | NFKB1BLMPMP22CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108366597-B | Substance mixture | 西姆莱斯有限公司 | 2022-09-02 | — | — | CN | claimed |
| EP-3383200-B1 | COMPOSITIONS | SYMRISE AG (DE) | 2019-11-06 | — | — | EP | claimed |
| US-20190289886-A1 | SUBSTANCE MIXTURES | SYMRISE AG (DE) | 2019-09-26 | — | — | US | claimed |
| EP-3470464-A1 | LAYER COMPOSITIONS WITH IMPROVED ELECTRICAL PARAMETERS COMPRISING PEDOT/PSS AND A STABILIZER | Heraeus Deutschland GmbH & Co KG (DE) | 2019-04-17 | — | — | EP | claimed |
| EP-2008530-B1 | Aroma composition for reducing or suppressing unwanted bitter and astringent impressions | SYMRISE AG (DE) | 2011-01-19 | — | — | EP | claimed |
| US-20080317923-A1 | AROMA COMPOSITION FOR REDUCING OR SUPPRESSING AN UNDESIRED BITTER, ASTRINGENT IMPRESSION | SYMRISE GMBH & CO. KG (DE) | 2008-12-25 | — | — | US | claimed |
| US-20080214675-A1 | Hydroxybenzoic Acid Amides and the Use Thereof For Masking Bitter Taste | SYMRISE GMBH & CO. KG (DE) | 2008-09-04 | — | — | US | claimed |
| EP-3911172-B1 | COMBINATION OF SATIETY COMPONENTS WITH ARGININE | SYMRISE AG (DE) | 2026-04-15 | — | — | EP | disclosed |
| EP-3823455-B1 | COMPOSITION FOR SUBSTITUTING SUGAR IN BAKED GOODS | SYMRISE AG (DE) | 2025-10-01 | — | — | EP | disclosed |
| US-20250163006-A1 | New Coolants, and Preparations Containing Same | SYMRISE AG (DE) | 2025-05-22 | — | — | US | disclosed |
| US-20250066320-A1 | Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same | SYMRISE AG (DE) | 2025-02-27 | — | — | US | disclosed |
| WO-2025026525-A1 | HETEROCYCLIC COMPOUNDS AS PHYSIOLOGICAL COOLANTS | SYMRISE AG (DE) | 2025-02-06 | — | — | WO | disclosed |
| EP-4469439-A1 | NEW COOLANTS, AND PREPARATIONS CONTAINING SAME | Symrise AG (DE) | 2024-12-04 | — | — | EP | disclosed |
| US-20080220140-A1 | USE OF PROPENYLPHENYL GLYCOSIDES FOR ENHANCING SWEET SENSORY IMPRESSIONS | SYMRISE GMBH & CO. KG (DE) | 2008-09-11 | — | — | US | disclosed |
| WO-2008046895-A1 | SUBSTITUTED BICYCLO[4.1.0]HEPTANE-7-CARBOXYLIC ACID AMIDES AND DERIVATIVES THEREOF AS FOOD FLAVOR SUBSTANCES | SYMRISE GMBH & CO. KG (DE) | 2008-04-24 | — | — | WO | disclosed |
| EP-1909599-A1 | USE OF HESPERETIN FOR ENHANCING THE SWEET TASTE | Symrise GmbH & Co. KG (DE) | 2008-04-16 | — | — | EP | disclosed |
| EP-1901618-A1 | HYDROXYPHENYLALKADIONES AND THEIR USE FOR MASKING BITTER TASTE AND/OR FOR INTENSIFYING SWEET TASTE | Symrise GmbH & Co. KG (DE) | 2008-03-26 | — | — | EP | disclosed |
| WO-2007107596-A1 | USE OF 4-HYDROXYDIHYDROCHALCONES AND THEIR SALTS FOR ENHANCING AN IMPRESSION OF SWEETNESS | SYMRISE GMBH & CO. KG (DE) | 2007-09-27 | — | — | WO | disclosed |
| WO-2007014879-A1 | USE OF HESPERETIN FOR ENHANCING THE SWEET TASTE | SYMRISE GMBH & CO. KG (DE) | 2007-02-08 | — | — | WO | disclosed |
| WO-2007003527-A1 | HYDROXYPHENYLALKADIONES AND THEIR USE FOR MASKING BITTER TASTE AND/OR FOR INTENSIFYING SWEET TASTE | SYMRISE GMBH & CO. KG (DE) | 2007-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066320-A1 | Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same | TAS2R5, TAS2R7, TAS2R8 | NFKB1 1617/4885BLM 4769/4885PMP22 1218/4885 |
| US-20250163006-A1 | New Coolants, and Preparations Containing Same | TTR, TAS2R5, TAS2R50 | NFKB1 3887/4885BLM 3313/4885PMP22 349/4885 |
| US-20190289886-A1 | SUBSTANCE MIXTURES | PNN, NISCH, HES1 | NFKB1 993/4885BLM 3586/4885PMP22 949/4885 |
| US-20080214675-A1 | Hydroxybenzoic Acid Amides and the Use Thereof For Masking Bitter Taste | TAS1R1, TAS2R1, TAS1R2 | NFKB1 623/4885BLM 3763/4885PMP22 2250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.