Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.30 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1763464 | 0.76 | NPC1 (0.38) | KDM4E | |
| SCHEMBL11407432 | 0.76 | XDH (0.30) | XDH | |
| SCHEMBL458710 | 0.76 | IMPDH2 (0.33) | IMPDH2 | |
| SCHEMBL10837168 | 0.74 | HCAR3 (0.51) | GABRA1GABRB2KDM4EALDH1A1MAPT | |
| SCHEMBL10837157 | 0.74 | HCAR3 (0.40) | HCAR3 | |
| Phenol SCHEMBL10346254 | 0.73 | CA12 (0.42) | XDHGABRA1GABRB2KDM4EMEN1 | |
| SCHEMBL175905 | 0.72 | — | — | |
| SCHEMBL10633551 | 0.71 | PDXK (0.34) | XDHGABRA1GABRB2KDM4EMEN1 | |
| SCHEMBL10998624 | 0.71 | IMPDH2 (0.35) | IMPDH2 | |
| SCHEMBL10824003 | 0.71 | KDM4E (0.42) | KDM4EMEN1ALDH1A1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502190-A | DEHYDROHALOGENATION IN THE PRESENCE OF PHASE TRANSFER CATALYST, SOLVENT AND ALKALI METAL HYDROXIDE | BAYER CORPORATION (US) | 1996-03-26 | — | — | US | claimed |
| US-5248776-A | Multistage reaction with sulfiding, cyclization and oxidative cleavage | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1993-09-28 | — | — | US | claimed |
| US-5189166-A | Vapor phase cyclization, dehydrogenation with manganese dioxide | DOWELANCO (US) | 1993-02-23 | — | — | US | claimed |
| WO-1992010496-A1 | ENANTIOMERICALLY PURE β-L-(-)-1,3-OXATHIOLANE NUCLEOSIDES | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1992-06-25 | — | — | WO | claimed |
| CN-110752298-B | Organic solar cell active layer based on hydroxypyrimidine derivative additive and preparation method thereof | 常州大学 | 2023-03-24 | — | — | CN | disclosed |
| CN-110752298-B | Organic solar cell active layer based on hydroxypyrimidine derivative additive and preparation method thereof | 常州大学 | 2023-03-24 | — | — | CN | disclosed |
| CN-110752298-A | Organic solar cell active layer based on hydroxypyrimidine derivative additive and preparation method thereof | 常州大学 | 2020-02-04 | — | — | CN | disclosed |
| CN-110752298-A | Organic solar cell active layer based on hydroxypyrimidine derivative additive and preparation method thereof | 常州大学 | 2020-02-04 | — | — | CN | disclosed |
| US-9828409-B2 | Bridged-cyclo-ProTides as prodrugs of therapeutic nucleosides and nucleotides | ZHONG MINGHONG (US) | 2017-11-28 | — | — | US | disclosed |
| US-20150266918-A1 | Bridged-Cyclo-ProTides as Prodrugs of Therapeutic Nucleosides and Nucleotides | ZHONG MINGHONG (US) | 2015-09-24 | — | — | US | disclosed |
| US-5502190-A | DEHYDROHALOGENATION IN THE PRESENCE OF PHASE TRANSFER CATALYST, SOLVENT AND ALKALI METAL HYDROXIDE | BAYER CORPORATION (US) | 1996-03-26 | — | — | US | disclosed |
| US-5248776-A | Multistage reaction with sulfiding, cyclization and oxidative cleavage | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1993-09-28 | — | — | US | disclosed |
| US-5189166-A | Vapor phase cyclization, dehydrogenation with manganese dioxide | DOWELANCO (US) | 1993-02-23 | — | — | US | disclosed |
| US-5189166-A | Vapor phase cyclization, dehydrogenation with manganese dioxide | DOWELANCO (US) | 1993-02-23 | — | — | US | disclosed |
| US-5189166-A | Vapor phase cyclization, dehydrogenation with manganese dioxide | DOWELANCO (US) | 1993-02-23 | — | — | US | disclosed |
| US-4729987-A | Insecticidal O,O-diethyl-O-(2-(1,1-dimethylethyl)-5-pyrimidinyl)-phosphorothioate | THE DOW CHEMICAL COMPANY (US) | 1988-03-08 | — | — | US | disclosed |
| US-4654329-A | Insecticidal, miticidal or nematocidal phosphorus esters of 5-pyrimidinols | THE DOW CHEMICAL COMPANY (US) | 1987-03-31 | — | — | US | disclosed |
| US-4486422-A | SYSTEMIC | THE DOW CHEMICAL COMPANY (US) | 1984-12-04 | — | — | US | disclosed |
| US-4429125-A | INSECTICIDES FOR APPLICATION TO SOILS | THE DOW CHEMICAL CO. (US) | 1984-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150266918-A1 | Bridged-Cyclo-ProTides as Prodrugs of Therapeutic Nucleosides and Nucleotides | TYMP, ENPP3, PNP | XDH 3495/4885GABRA1 4233/4885GABRB2 3918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.