Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB2 | P47870 | 11/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 10/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.44 |
| ▸ | GABRE | P78334 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24013805 | 0.88 | GABRG2 (0.44) | GABRB2GABRA2GABRG2GABRB3GABRA5 | |
| SCHEMBL30228350 | 0.88 | GABRG2 (0.44) | GABRB2GABRA2GABRG2GABRB3GABRA5 | |
| SCHEMBL30350059 | 0.83 | CYP11B2 (0.52) | GABRB2GABRA2GABRG2GABRB3GABRA5 | |
| SCHEMBL29276897 | 0.82 | GABRG2 (0.44) | GABRB2GABRA2GABRG2GABRB3GABRA5 | |
| SCHEMBL30292711 | 0.82 | GABRG2 (0.44) | GABRB2GABRA2GABRG2GABRB3GABRA5 | |
| SCHEMBL4833478 | 0.80 | GABRB2 (0.54) | GABRB2GABRA2CYP1A2GABRA1CYP2C19 | |
| SCHEMBL899733 | 0.79 | GABRA2 (0.47) | GABRB2GABRA2GABRG2GABRB3GABRA5 | |
| SCHEMBL32680189 | 0.78 | CYP1A2 (0.47) | GABRB2GABRA2CYP1A2GABRA1CYP2C19 | |
| SCHEMBL2071880 | 0.78 | CYP11B2 (0.46) | GABRB2GABRA2GABRG2GABRB3GABRA5 | |
| SCHEMBL25153554 | 0.74 | LMNA (0.51) | GABRB2GABRA2CYP1A2GABRA1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621907-A1 | FUNGICIDAL IMIDAZOLES | E.I. Du Pont De Nemours And Company (US) | 2013-08-07 | — | — | EP | disclosed |
| US-20130143929-A1 | FUNGICIDAL IMIDAZOLES | EI DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-06 | — | — | US | disclosed |
| WO-2012044650-A1 | FUNGICIDAL IMIDAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130143929-A1 | FUNGICIDAL IMIDAZOLES | CYP1A1, CYP1B1, CYP2E1 | GABRB2 2523/4885GABRA2 2813/4885GABRG2 2455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.