Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 10/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 10/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 9/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 9/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 9/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.47 |
| ▸ | GABRD | O14764 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GABRE | P78334 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL898846 | 0.81 | MARS1 (0.38) | GABRA2GABRB2GABRG2GABRB3GABRA5 | |
| SCHEMBL899764 | 0.81 | GABRG2 (0.38) | GABRG2GABRB3GABRA5MEN1CYP1A2 | |
| SCHEMBL899443 | 0.79 | GABRB2 (0.44) | GABRA2GABRB2GABRG2GABRB3GABRA5 | |
| SCHEMBL899830 | 0.78 | HTT (0.40) | CYP2D6SMN1; SMN2 | |
| SCHEMBL900038 | 0.77 | ALDH1A1 (0.41) | TSHRMEN1ALDH1A1CYP1A2KMT2A | |
| SCHEMBL20027601 | 0.75 | ALDH1A1 (0.55) | GABRA2GABRB2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL25342734 | 0.74 | GABRA2 (0.44) | GABRA2GABRB2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL14692599 | 0.71 | PDE4B (0.46) | GABRA5TSHRGABRA1MEN1ALDH1A1 | |
| SCHEMBL899604 | 0.71 | TSHR (0.38) | GABRA2GABRB2GABRG2GABRB3GABRA5 | |
| SCHEMBL23354645 | 0.71 | GABRA2 (0.44) | GABRA2GABRB2TSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621907-A1 | FUNGICIDAL IMIDAZOLES | E.I. Du Pont De Nemours And Company (US) | 2013-08-07 | — | — | EP | disclosed |
| US-20130143929-A1 | FUNGICIDAL IMIDAZOLES | EI DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-06 | — | — | US | disclosed |
| WO-2012044650-A1 | FUNGICIDAL IMIDAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130143929-A1 | FUNGICIDAL IMIDAZOLES | CYP1A1, CYP1B1, CYP2E1 | GABRA2 2813/4885GABRB2 2523/4885GABRG2 2455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.