Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7212732 | 0.84 | KMT2A (0.51) | KMT2AMEN1HTTL3MBTL1MAPT | |
| SCHEMBL7707969 | 0.83 | ALDH1A1 (0.39) | KMT2AMEN1HTTL3MBTL1MAPT | |
| SCHEMBL6130205 | 0.83 | KMT2A (0.48) | KMT2AMEN1HTTL3MBTL1MAPT | |
| SCHEMBL8994708 | 0.81 | KMT2A (0.49) | KMT2AMEN1HTTL3MBTL1MAPT | |
| SCHEMBL6130232 | 0.76 | HTT (0.46) | KMT2AMEN1HTTL3MBTL1MAPT | |
| SCHEMBL14754995 | 0.74 | KMT2A (0.62) | KMT2AMEN1HTTL3MBTL1MAPT | |
| SCHEMBL14259711 | 0.74 | KMT2A (0.60) | KMT2AMEN1HTTL3MBTL1MAPT | |
| SCHEMBL7615988 | 0.73 | KMT2A (0.50) | KMT2AMEN1HTTL3MBTL1MAPT | |
| SCHEMBL4445330 | 0.73 | KMT2A (0.50) | KMT2AMEN1HTTL3MBTL1MAPT | |
| SCHEMBL7622693 | 0.71 | TUBB4A (0.49) | KMT2AMEN1HTTL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488172-A | Chiral phosphorus compounds | HOFFMANN-LA ROCHE INC. (US) | 1996-01-30 | — | — | US | disclosed |