Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15700139 | 0.79 | ALDH1A1 (0.47) | HSD11B1CYP3A4PDE4APDE4BPDE4C | |
| SCHEMBL8998992 | 0.76 | MMP8 (0.49) | CYP3A4CYP2C19ALDH1A1MEN1KMT2A | |
| SCHEMBL1332360 | 0.75 | ALDH1A1 (0.51) | HSD11B1ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL3625848 | 0.75 | ALDH1A1 (0.51) | HSD11B1ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL1184723 | 0.74 | ALDH1A1 (0.50) | HSD11B1ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL31483318 | 0.74 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2ANPSR1KDM4E | |
| SCHEMBL917955 | 0.74 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2ANPSR1KDM4E | |
| SCHEMBL11590919 | 0.74 | ALDH1A1 (0.50) | HSD11B1ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL5084136 | 0.74 | LMNA (0.55) | CYP3A4ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8998813 | 0.73 | MMP8 (0.47) | CYP3A4CYP2C19ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10696617-B2 | Method for alcoholysis of amide | ASYMCHEM LABORATORIES (TIANJIN) CO., LTD (CN) | 2020-06-30 | — | — | US | disclosed |
| US-20200055807-A1 | METHOD FOR ALCOHOLYSIS OF AMIDE | ASYMCHEM LABORATORIES (TIANJIN) CO., LTD (CN) | 2020-02-20 | — | — | US | disclosed |
| CN-107417594-A | A kind of method of acid amides alcoholysis | 凯莱英医药集团（天津）股份有限公司 | 2017-12-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055807-A1 | METHOD FOR ALCOHOLYSIS OF AMIDE | ADH1A, ADH5, ADH1C | HSD11B1 779/4885CYP3A4 500/4885CYP2C19 1088/4885 |
| US-10696617-B2 | Method for alcoholysis of amide | ADH5, ADH1A, ADH1C | HSD11B1 766/4885CYP3A4 267/4885CYP2C19 608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.