Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9000599 | 0.93 | SOAT1 (0.40) | SOAT1 | |
| SCHEMBL9000513 | 0.89 | SOAT1 (0.41) | SOAT1MAPTRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL9000798 | 0.89 | QPCT (0.49) | SOAT1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL9000758 | 0.89 | SOAT1 (0.41) | SOAT1MAPTKMT2ACNR2MEN1 | |
| SCHEMBL9000450 | 0.89 | SOAT1 (0.41) | TRPV1SOAT1MAPTKMT2AMEN1 | |
| SCHEMBL9000612 | 0.88 | GCGR (0.44) | SOAT1MAPT | |
| SCHEMBL9000864 | 0.85 | ALDH1A1 (0.49) | MAPTKMT2ACNR2IGF1RMEN1 | |
| SCHEMBL9000398 | 0.85 | EPHX1 (0.47) | SOAT1MAPTKMT2ACNR2IGF1R | |
| SCHEMBL9000825 | 0.85 | GLI1 (0.39) | SOAT1KMT2AMEN1 | |
| SCHEMBL9000846 | 0.85 | SOAT1 (0.40) | SOAT1MAPTKMT2AMEN1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583147-A | INHIBITORS OF ACYL-COENZYME A: CHOLESTEROL O-TRANSFERASE; ANTIHYPERCHOLESTEROLEMIC AND/OR ANTIATHEROSCLEROTIC AGENTS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-12-10 | — | — | US | disclosed |