Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9000954 | 0.89 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1KMT2ALMNASLC2A1 | |
| SCHEMBL9000864 | 0.87 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1KMT2ASLC2A1MEN1 | |
| SCHEMBL9000496 | 0.85 | MAPT (0.44) | SMN1; SMN2ALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL9000758 | 0.85 | SOAT1 (0.41) | SMN1; SMN2ALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL9000753 | 0.83 | SOAT1 (0.39) | SMN1; SMN2ALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL9000777 | 0.79 | KMT2A (0.37) | KMT2ALMNAMEN1SOAT1CNR2 | |
| SCHEMBL9000815 | 0.79 | MAPT (0.50) | SMN1; SMN2ALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL9000853 | 0.78 | SOAT1 (0.42) | SMN1; SMN2ALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL9000608 | 0.78 | FNTA (0.37) | KMT2ALMNASOAT1NPSR1 | |
| SCHEMBL9000887 | 0.78 | LMNA (0.39) | SMN1; SMN2KMT2ALMNAMEN1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583147-A | INHIBITORS OF ACYL-COENZYME A: CHOLESTEROL O-TRANSFERASE; ANTIHYPERCHOLESTEROLEMIC AND/OR ANTIATHEROSCLEROTIC AGENTS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-12-10 | — | — | US | disclosed |