Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 5/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9000603 | 0.96 | SOAT1 (0.35) | SOAT1MEN1KMT2AMAPK1RAB9A | |
| SCHEMBL9000777 | 0.93 | KMT2A (0.37) | SOAT1MEN1KMT2APOLB | |
| SCHEMBL9000831 | 0.90 | TOP2A (0.37) | SOAT1MEN1KMT2APOLBRAB9A | |
| SCHEMBL9000753 | 0.88 | SOAT1 (0.39) | SOAT1MEN1KMT2APOLBRAB9A | |
| SCHEMBL9000768 | 0.87 | EPHX1 (0.41) | — | |
| SCHEMBL9000701 | 0.87 | EPHX1 (0.41) | SOAT1MEN1KMT2APOLB | |
| SCHEMBL9000915 | 0.87 | SOAT1 (0.44) | SOAT1MAPK1RAB9A | |
| SCHEMBL9000769 | 0.86 | SOAT1 (0.44) | SOAT1MEN1KMT2APOLB | |
| SCHEMBL9000608 | 0.85 | FNTA (0.37) | SOAT1P2RX3KMT2A | |
| SCHEMBL9000722 | 0.85 | SMN1; SMN2 (0.36) | P2RX3MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583147-A | INHIBITORS OF ACYL-COENZYME A: CHOLESTEROL O-TRANSFERASE; ANTIHYPERCHOLESTEROLEMIC AND/OR ANTIATHEROSCLEROTIC AGENTS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-12-10 | — | — | US | disclosed |