Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 7/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.33 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9000610 | 0.96 | CTRC (0.39) | SOAT1RAB9AMAPK1MEN1KMT2A | |
| SCHEMBL9000915 | 0.91 | SOAT1 (0.44) | SOAT1RAB9AMAPK1SOAT2ACAT1 | |
| SCHEMBL9000745 | 0.87 | EPHX1 (0.41) | SOAT1RAB9AMEN1KMT2AGAA | |
| SCHEMBL9000777 | 0.87 | KMT2A (0.37) | SOAT1MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL9000722 | 0.87 | SMN1; SMN2 (0.36) | RAB9AMAPK1ACAT1MAPTNPC1 | |
| SCHEMBL9000714 | 0.86 | GPR88 (0.39) | SOAT1RAB9AMEN1KMT2ASOAT2 | |
| SCHEMBL9000888 | 0.86 | EPHX1 (0.44) | SOAT1 | |
| SCHEMBL9000423 | 0.86 | EPHX1 (0.44) | SOAT1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL9000651 | 0.85 | SOAT1 (0.41) | SOAT1SMN1; SMN2CYP1A2 | |
| SCHEMBL9000831 | 0.85 | TOP2A (0.37) | SOAT1RAB9AMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583147-A | INHIBITORS OF ACYL-COENZYME A: CHOLESTEROL O-TRANSFERASE; ANTIHYPERCHOLESTEROLEMIC AND/OR ANTIATHEROSCLEROTIC AGENTS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-12-10 | — | — | US | disclosed |